10 - ANTIHYPERLIPIDEMICS

Item Number: 11822 correct answer: 4 category: Antihyperlipidemics

1. An agent primarily used to decrease triglycerides is:

1. lovastatin

2. neomycin

3. cholestyramine

4. gemfibrozil

5. probucol

Item Number: 11824 correct answer: 5 category: Antihyperlipidemics

2. Gallstones, abdominal pain and myalgia are side effects of:

1. colestipol

2. probucol

3. lovastatin

4. nicotinic acid

5. clofibrate

Item Number: 11836 correct answer: 4 category: Antihyperlipidemics

3. Correct statements regarding the effects of lipid lowering agents on serum

lipids include:

1. nicotinic acid reduces VLDL triglycerides only

2. probucol increases HDL

3. neomycin increases LDL cholesterol

4. clofibrate primarily decreases VLDL triglycerides

5. lovastatin decreases HDL

Item Number: 11418 correct answer: 3 category: Antihyperlipidemics

4. Drugs which indirectly enhance the activity of the hepatic enzyme HMG CoA

reductase include:

1. probucol

2. D-thyroxine

3. cholestyramine

4. lovastatin

5. gemfibrozil

Item Number: 11821 correct answer: 1 category: Antihyperlipidemics

5. Agents primarily used to treat hypercholesterolemia which work by inhibiting

the HMG-CoA reductase enzyme include:

1. lovastatin

2. gemfibrozil

3. niacin

4. clofibrate

5. colestipol

Item Number: 11413 correct answer: 4 category: Antihyperlipidemics

6. Niacin is a hypolipidemic drug which has several adverse effects.

Administration of an aspirin 30 minutes prior to a dose reduces the likelihood

of:

1. elevated hepatic enzymes

2. diarrhea

3. acanthosis nigricans

4. cutaneous flushing

5. myositis

Item Number: 11826 correct answer: 5 category: Antihyperlipidemics

7. Side effects of niacin include:

1. flushing

2. hyperglycemia

3. jaundice

4. hyperuricemia

5. All of the above

Item Number: 11838 correct answer: 2 category: Antihyperlipidemics

8. The agent which is thought to lower triglycerides by inhibiting hepatic VLDL

secretion and suppressing VLDL synthesis is:

1. neomycin

2. nicotinic acid

3. fluvastatin

4. colestipol

5. beta sitosterol